Call for an instant quote 0345 90 80 161
Open Mon to Fri 09:00 - 17:30 | Sat 09:00 - 16:00 (GMT)
11 April 2018 09:03
Scientists have announced their latest breakthrough in the battle against Alzheimer's disease
Scientists have announced their latest breakthrough in the battle against Alzheimer's disease, after neutralising a high-risk gene in a human brain cell for the first time.
A California-based team successfully identified the responsible protein (associated with the apoE4 gene) and then succeeded in stopping it from damaging human neuron cells.
New potential
The study could mean new potential for halting the disease, though scientists are keen to take the research one step at a time, as, so far, their compound has only been tried on cells in a laboratory.
People with one copy of the apoE4 gene are twice as likely to develop Alzheimer's disease, while having two copies increases the risk 12-fold.
According to previous studies, roughly one in four people have the gene, which creates a misshapen protein that breaks down into disease-causing fragments in the cells.
This results in the development of problems commonly associated with Alzheimer's disease, which affects about 7.1% of Britons over the age of 65.
Next steps
The researchers are now working with the pharmaceutical industry to improve the compounds they've developed in order to test them on human beings.
Yadong Huang, who led the study, which is published in Nature Medicine, said: "Drug development for Alzheimer's disease has been largely a disappointment over the last 10 years.
"Many drugs work beautifully in a mouse model, but so far they've all failed in clinical trials.
"One concern within the field has been how poorly these mouse models really mimic human disease."
Huang and his colleagues went straight for human brain cells rather than the traditional mouse trial because they realised the presence of the apoE4 gene does not change the production of amyloid beta in a mouse brain.
Last month senior British scientists predicted that within the next few decades Alzheimer's sufferers will be able to live with the disease without the devastating symptoms.
If you're travelling with a family member suffering from Alzheimer's, don't forget to sort the specific insurance package to cover them.
21 April 2018
Heart attack patients should be prescribed exercise to reduce their risk of death, researchers suggest.
[more...]
19 April 2018
A self-injected smart drug may be the key to easing and preventing pain for migraine sufferers.
17 April 2018
Simple brain-training exercises carried out at home have been shown to reduce emotional stress in female breast cancer survivors, it's recently been revealed.
13 April 2018
Drinkers who consume more alcohol than UK guidelines suggest could be cutting years off their lives, according to new research.
12 April 2018
A recent study has revealed that people who sustain brain injuries are at an increased risk of developing dementia later in life.
11 April 2018
07 April 2018
The Philippines is set to shut its most famous holiday island of Boracay for six months, after the President described it as a "cesspool".
05 April 2018
Taxes on soft drinks, alcohol and tobacco - nicknamed "sin taxes" - could be a powerful step towards combating rising rates of chronic diseases worldwide, research has suggested.
New "one-stop shops" to speed up cancer diagnosis are being trialled across the country for the first time.
30 March 2018
Doctors should tell patients that e-cigarettes are less harmful than smoking but not without risk, according to new national guidance.
29 March 2018
Young people suffering from mental health problems are finding it hard to get the support they need, a survey has revealed.
28 March 2018
Children exposed to epilepsy drugs in the womb may achieve poorer test results at school, a study has suggested.