Call for an instant quote
0345 90 80 161
Open Mon to Fri 09:00 - 17:30 | Sat 09:00 - 16:00 (GMT)
28 January 2014 08:57
Researchers are now working with a biotechnology company to prepare the experimental drug for patient trials
An experimental drug that researchers say can virtually halt the spread of breast cancer has given fresh hope to sufferers of the disease.
Scientists from Cardiff University's European Cancer Stem Cell Research Institute have found that the chemical compound in question suppresses a gene called Bc13, which appears to play a critical role in metastasis.
They conducted computer simulations to work out how Bc13 functioned and then blocked it in tests on mice using a compound identified from a "virtual library" of chemicals.
The spread of tumours to vital organs such as the liver, brain and lungs is the chief reason why people die from cancer.
In the case of breast cancer, as many as 12,000 women in the UK develop a metastatic disease each year - often several years after their initial diagnosis.
"Despite great improvements in therapy of early stage breast cancer, the current therapeutic options for patients with late stage metastatic disease are limited," said Dr Richard Clarkson, who was part of the research team.
"There is therefore a clear unmet clinical need to identify new drugs to reverse or at least to slow down disease progression."
When mice with metastatic breast cancer were treated with the compound, the spread of tumours to the lungs and other parts of the body was dramatically reduced. In some cases, suppressing Bc13 meant the spread of cancer was halted by more than 80%.
Breast cancer is the most common cancer in the UK. It mostly affects women over the age of 50, although younger women, and in rare cases, men, can also develop the disease.
Sufferers holidaying overseas should remember to purchase adequate
breast cancer travel insurance before jetting off, just in case something unexpected happens.
Following the successful testing on groups of mice, the scientists are now working with a UK-based biotechnology company called Tiziana Pharmaceuticals to further develop the drug and eventually bring it to clinical trials.
27 September 2016
Monarch Airlines says its flights are operating as normal amid fears the firm is in financial trouble.
24 September 2016
Slim people who look physically healthy may still be at increased chance of being diagnosed with bowel cancer if they have raised insulin levels, according new research.
23 September 2016
Theresa May is being urged to give the go-ahead for flights to resume between the UK and Sharm el-Sheikh by the head of the cross-party parliamentary group on Egypt.
22 September 2016
Budget airline Jet2.com is to open its first base in the south of England at Stansted.
21 September 2016
Smoking rates have dropped to the lowest level on record in England, new figures show, suggesting messages about the health effects of cigarettes are hitting home.
20 September 2016
Concerns have been raised over flight disruptions caused by heavy drinking among passengers.
17 September 2016
British Airways' decision to launch direct flights from London to Tehran earlier this month positions Iran as one of the hottest destinations to visit in 2017, according to experts.
16 September 2016
More than 100 flights have been cancelled as French air traffic controllers go on strike again.
15 September 2016
Two thirds of MPs would support an expansion at Heathrow.
14 September 2016
TripAdvisor is launching a new homepage, making the booking of holiday activities and tours even easier.
13 September 2016
Travellers are to be charged to use fast lanes to get through passport checks in an attempt to cut queues.
09 September 2016
People travelling to regions affected by the Zika virus outbreak should practise safe sex for at least half a year upon their return, health leaders say.