Call for an instant quote
0345 90 80 161
Open Mon to Fri 09:00 - 17:30 | Sat 09:00 - 16:00 (GMT)
28 January 2014 08:57
Researchers are now working with a biotechnology company to prepare the experimental drug for patient trials
An experimental drug that researchers say can virtually halt the spread of breast cancer has given fresh hope to sufferers of the disease.
Scientists from Cardiff University's European Cancer Stem Cell Research Institute have found that the chemical compound in question suppresses a gene called Bc13, which appears to play a critical role in metastasis.
They conducted computer simulations to work out how Bc13 functioned and then blocked it in tests on mice using a compound identified from a "virtual library" of chemicals.
The spread of tumours to vital organs such as the liver, brain and lungs is the chief reason why people die from cancer.
In the case of breast cancer, as many as 12,000 women in the UK develop a metastatic disease each year - often several years after their initial diagnosis.
"Despite great improvements in therapy of early stage breast cancer, the current therapeutic options for patients with late stage metastatic disease are limited," said Dr Richard Clarkson, who was part of the research team.
"There is therefore a clear unmet clinical need to identify new drugs to reverse or at least to slow down disease progression."
When mice with metastatic breast cancer were treated with the compound, the spread of tumours to the lungs and other parts of the body was dramatically reduced. In some cases, suppressing Bc13 meant the spread of cancer was halted by more than 80%.
Breast cancer is the most common cancer in the UK. It mostly affects women over the age of 50, although younger women, and in rare cases, men, can also develop the disease.
Sufferers holidaying overseas should remember to purchase adequate
breast cancer travel insurance before jetting off, just in case something unexpected happens.
Following the successful testing on groups of mice, the scientists are now working with a UK-based biotechnology company called Tiziana Pharmaceuticals to further develop the drug and eventually bring it to clinical trials.
27 April 2017
The port city of Liverpool is to be the starting point of the biggest round the world ocean race.
26 April 2017
Nearly three-quarters of patients diagnosed with cancer in A&E had previously seen their GP with related symptoms, according to research.
25 April 2017
Researchers recently suggested cycling could reduce the risk of cancer - and now a campaign has launched urging people to get on two wheels.
22 April 2017
The flag for Britain will be flown on a global scale at the forthcoming Clipper Round the World Race.
21 April 2017
Want to lower your risk of suffering cancer or heart disease? Then get on your bike.
20 April 2017
Researchers have made a significant breakthrough in understanding the way in which breast cancer grows and spreads.
19 April 2017
Budget airline easyJet has apologised over an incident in which two passengers were ordered to leave an overbooked flight.
14 April 2017
Holidays have topped the priority lists of people approaching retirement, with close to two thirds (64%) aiming to go on more trips once they leave the world of work behind.
13 April 2017
A major bank has outlined plans to become more "dementia-friendly".
12 April 2017
Restrictions should be put in place to curb the drinking of alcohol before early-morning flights, a House of Lords committee has suggested.
11 April 2017
Drivers heading to airports and ferry ports this bank holiday weekend have been told to expect heavy traffic.
People who are beginning to notice signs of grey hair have more to worry about than their image.